2 comments on “Evaluating Donations to Cure Aging

  1. Thanks for writing this up. One factor you should consider in deciding whether to donate to LRI is that the ease with which the highest-integrity current programs attract funding will likely affect potential founders’ perceived prospects of success starting a charity with the desired higher-potential approach. Since you’re not the only donor in the space, you might want to consider either giving to LRI on the general principle of encouraging good anti-aging research programs, or try to leverage your giving more by actively seeking out potential founders of organizations following approaches you think have more potential and offering them initial funding.

  2. The reason why people are interested in the LRI is because it’s run by Sarah Constantin, a well-known member of the rationalist community. Unfortunately, an objective evaluation of the programs implemented by the LRI suggest that the expected value of an investment in the LRI is approximately zero.

    Only an idiot would invest money in trying to reproduce an implausibly effective Russian study concerning supplementation of a neuropeptide in mice. Sorry, but anyone with even moderate knowledge of the history of drug development or murine studies would agree. It is effectively worthless.

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