Bayesian Investor Blog

In early April I started measuring my diet fairly carefully (using CRON-O-Meter). It is a somewhat tedious project, but it has has shown me that I’m getting too much Omega-6.

Most of the discussion I’d previously noticed implied that I should improve my Omega-6/Omega-3 ratio by consuming more Omega-3.

But after finding Dave Asprey’s website and hearing him at the Personalized Life Extension Conference, his framing of the issue as Omega-6 poisoning led me to look more carefully at my Omega-6 consumption, and is one of the reasons I tried CRON-O-Meter.

There are conflicting opinions about what ratio people ought to aim for, but those who advocate a ratio close to 1:1 seem to have a good theory (resemblance to hunter-gatherer diets), while I suspect those who advocate much higher Omega-6 levels either assume it’s hopeless to convince many people to achieve a ratio anywhere near 1:1 or have motives unrelated to Omega-fats for pushing oils with a high Omega-6 to Omega-3 ratio.

So my guess is that I should aim for a ratio less than 2:1, and be concerned if my ratio exceeds 3:1.

Even with fairly drastic changes to my diet (virtually eliminating canola oil and olive oil, and cutting back on my peanut addiction by an order of magnitude), I still find that it takes careful thought to keep my daily Omega-6 consumption below 10 grams.

I could in principle take a dozen or more fish oil pills to offset the Omega-6, but the safety of taking over 6 grams of Omega-3 per day seems unknown.

So I am working on switching to foods that have fat that’s very low in Omega-6, mainly coconut oil and butter from grass-fed cows (Kerrygold is the widely available brand).

That mostly doesn’t require eating food that’s less tasty (Kerrygold butter tastes better than most other fats), but it reduces the variety of foods I can eat. It rules out what I used to consider ordinary amounts of most nuts, and many processed foods (Trader Joes’ eggplant and red pepper spreads looked like a convenient way to get veggies until I quantified the effect of the sunflower oil that is the fourth ingredient in each).

I’ll try to post some of my best recipes in a few months.

For more references, see this pubmed entry and Wikipedia.

The Personalized Life Extension Conference 2012 presented lots of ideas, with occasionally some science to back them up.

A lot of the advice backed up by the best science won’t be followed. In spite of the title of Brian Delaney’s Calorie Restriction talk, he didn’t have a solution to the problem of feeling hungry. When Max Peto reminded us of the dangers of sitting, the percentage of people who remained seated only dropped from maybe 97 to 95. There were vendors pushing food that had higher than optimal sugar content, and I think at least one pusher had some success.

I’ve been cutting back drastically on my vitamin/supplement consumption, and Stephen Spindler’s talk (arguing that most apparently good results in other animals were due to supplements inducing calorie restriction) has me thinking about cutting back farther to just fish oil and vitamin D.

The telomere guys still haven’t come up with a good theory for why evolution didn’t do the apparently easy thing and make some telomerase available to non stem cells, so I’m still assuming there’s some tradeoff such as cancer.

The most interesting talk was by David Asprey, describing an “upgraded paleo” diet – high fat, with careful attention to the quality of the fat. He has more ideas than he has time to communicate them.

Unfortunately he seems too busy throwing out new opinions to document the evidence behind them (or maybe the evidence is hiding somewhere on his poorly organized website). But in most cases he has a plausible paleo-like theory, and I’m generally confident they’d be little worse than a placebo, so I’m trying some of them.

At the moment that involves consuming more of some paleo-like foods that I’d already been starting to add to my diet. Grass-fed (Kerrygold) butter is possibly the most important, and coconut products are also rather high on the list. The butter tastes better than my dim recollection of butter from malnourished grain-fed cows. Coconut milk works well as a substitute for milk in dishes such as chowder and cream of onion soup.

Josh Whiton had an intriguing idea about trying to get the benefits of calorie restriction via a very low protein diet once or twice a week (with a paleo-like diet the rest of the time).

A protein rich diet may make us more alert and help us lose weight.

The reaction of Hypothalamic orexin/hypocretin neurons to amino acids (especially nonessential amino acids) appears to be a mechanism for this effect.

Poultry products appear to be one of the better ways to get nonessential amino acids.

I’ve been trying to increase the protein in my diet for the past four months (in response to weaker evidence than I’ve linked to here), and have found that animal sources have been the easiest way to do that (I’ve mainly increased my egg and meat consumption). I think I’ve found it slightly easier to avoid gaining weight. I think I’ve also been more alert, but I don’t think the increase in alertness coincided too closely with the increase in protein consumption.